The league announced that 42 cases were recorded on Monday morning, with Manchester United's game against Brentford postponed as a result.
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The Premier League fear the league could be suspended, amid rising cases of Covid among players competing at England's highest football level.
The league announced that 42 cases were recorded on Monday morning, with Manchester United's game against Brentford postponed as a result.
Low vaccination rates among the players, which has resulted in players facing a lengthy wait for the booster jab, needed to help protect against the Omicron variant, after some studies showed that two jabs offer little immunity.
The Daily Mail has learned that Wolves are the only club who will have all over-18s receiving their third vaccine before the end of the month.
Tottenham's clash against Brighton was postponed on Sunday after a Covid outbreak hit the club camp.
As well as having their game against Brentford postponed, Manchester United have also closed their Carrington Training Ground on Monday due to Coronavirus cases.
Furthermore,
The NHS will need to exceed 840,000 booster jabs per day in a bid to fight Omicron, which is causing around 200,000 new infections per day, the Health Secretary has said.
Sajid Javid told MPs that every adult across England could expect to be offered a “chance to get boosted by the end of this month” though he suggested not everyone would get a dose in December.
He said: “It is asking a huge amount of our colleagues in the NHS.
“And it’s our joint view that we can try to offer adults a chance to get boosted by the end of this month.
“And that does not mean every single person necessarily can get that booster, it requires them to come forward and to take up this offer as well, as well as everything going right in this huge expansion plan.”