Statins and their side effects: Doctor shares how to minimise reactions and when to 'seek medical attention'

How you take statins could determine whether you experience side effects
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If you're starting atorvastatin for the first time, it's completely normal to notice a few minor niggles during those initial couple of weeks on the medication.
Dr Blen Tesfu, Physician and Medical Advisor with Welzo, explains that new patients often experience some light muscle aching, gentle headaches, a bit of stomach discomfort, and feeling more tired than usual.
Generally, these side effects are taken as your body's way of getting used to the cholesterol-lowering process that atorvastatin kicks off. When side effects persist, however, it may be worth speaking to a doctor.
"The majority of patients do not need any intervention as their side effects tend to subside on their own, which is particularly true if the patient takes their medication daily at the same time every day," Dr Tesfu told GB News.
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Taking statins at the same time every day can lower the risk of side effects
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"Additionally, hydration and limiting the number of prescription medications used (if possible) may also help alleviate the symptoms experienced by the patient.
"If the patient experiences significant muscle aches, muscle aches that continue over an extended period of time, and/or if muscle aches are accompanied by weakness and/or dark colored urine, then the patient should seek medical attention.
"If the patient continues to experience prolonged episodes of nausea, has yellow discolouration of the skin, or feels excessively tired, the patient should also seek medical attention."
To minimise adverse reactions, take your tablet at the same time each day to help your body settle into a routine.
Staying well hydrated can also make a difference when it comes to easing any discomfort you might feel.
If you're on other prescription medications, it's worth having a chat with your doctor about whether any can be reduced, as this may help too.
The key thing is patience, noted Dr Tesfu, as your system just needs a little time to adjust to the new medication.
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Feeling absolutely exhausted beyond what's normal for those early adjustment weeks is also something to flag with a healthcare.
How long does it take for statins to work?
While patients won't physically feel any different, atorvastatin gets to work quickly behind the scenes.
LDL cholesterol levels typically drop within about four weeks, making a significant difference to heart health.

Statins make a significant difference to cholesterol levels over time
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This early reduction matters because LDL plays a big role in plaque building up in your arteries, so getting those levels down helps protect your blood vessels.
When asked why some people breeze through statin therapy while others find it trickier, Dr Tesfu explained that individual factors like age, genetic makeup, any existing liver or muscle conditions, the dose you're on, and how the medication interacts with other drugs you might be taking.
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