The Met Office has issued an urgent yellow weather warning with up to 10cm of snow set to fall overnight.
Parts of northern and central Scotland are set to be covered during the early hours of Friday morning as the warning remains in place from 3am to 9am.
The weather agency warn that the wintry conditions are likely to cause some travel disruption on Friday morning.
Regions affected include Central, Tayside and Fife, Grampian, Highlands and Eilean Siar and Strathclyde.
The Met Office has issued an urgent yellow weather warning as up to 10cm of snow is set to fall overnightWXCHARTSA Met Office spokesperson said: "Snow is expected to develop, particularly over higher ground, during the early hours of Friday before easing during the morning.
"Accumulating snow is expected to mainly occur above around 200 metres, with a chance of temporary accumulations below this where precipitation becomes temporarily heavy.
"2-5 cm of snow is expected fairly widely above 250 metres with a chance that a few places within the warning area at lower levels could see a few cm settle.
"Accumulations of 10 cm or more are expected to be reserved for above 300 metres."
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Another yellow weather warning for rain has also been issued and will remain in place from 2am until 9am on Friday.
Heavy rain is expected to impact a number of towns and cities in the north of Scotland including Edinburgh, Glasgow, and Stirling.
A spokesperson said: "Heavy rain is expected to develop across the Central Belt on Thursday night before clearing on Friday morning.
"Many areas are likely to see 15-25 mm of rain, much of this falling in around 6 hours with a few locations seeing up to 35 mm overnight."
Parts of northern and central Scotland are set to be covered during the early hours of Friday morning as the warning remains in place from 3am to 9am
Met Office
Forecasters expect conditions to become windy over the weekend with a yellow weather warning for wind in place from 8am until 10pm on Saturday.
The Met Office say a deep area of low pressure will bring a spell of very windy weather to western areas.
The weather agency said: "Gusts of 50 mph are expected quite widely on Saturday, while some exposed spots, particularly on the coast, will see 60 to 70 mph gusts with large waves also likely."