Ambulance crews have been called to the scene of a train derailment in Cumbria.
The Avanti West Coast train, travelling from Glasgow to Euston, left the tracks near Shap at around 6.10am today.
North West Ambulance Service said it has sent "resources" to the scene of the incident.
Other emergency services are said to be at the scene.
The ambulance service said in a statement: "Following reports of a train derailment near Shap in Cumbria, the trust has dispatched resources to the scene.
"We are currently assessing the situation and working with other members of the emergency services.
"Our priority is to ensure people receive the medical help they need as quickly as possible."
Transport Secretary Heidi Alexander said a major incident had been declared but said "there are no reported injuries".
LATEST DEVELOPMENTS:
Transport Secretary Heidi Alexander said a major incident had been declared
|@THEBOYO10/GB NEWS
She told LBC Radio: "We will work swiftly to make sure that people can get off the train safely.
"I will be remaining in constant touch with the train operating company and the railway accident investigation branch."
Avanti West Coast confirmed one of its trains was involved in the incident.
A spokesman for the rail firm said: "At 6.19am today, November 3, the 4.28am Avanti West Coast service from Glasgow to Euston was reported to have derailed at Shap in Cumbria.
There are said to be no reported injuries after the train left the trains near Shap in Cumbria
| GOOGLE"Our priority is the wellbeing of everyone who was board and getting them safely off the train. We are assisting emergency services who are on the scene.
"As a result, all lines are blocked north of Preston. Please do not attempt to travel north of Preston today.
"We’ll provide further information in due course, but it is likely there will be significant disruption to our network for a number of days."
National Rail has warned passengers of disruption to rail services running between Carlisle and Preston until the end of the day.
Avanti West Coast has confirmed one of its trains was involved in the incident (file photo)
|GETTY
"Trains running between Carlisle and Preston may be delayed by up to 120 minutes or cancelled," it said.
"Major disruption is expected until the end of the day."