Calum Best has revealed that his mother Angie has been diagnosed with colon cancer that has spread to her liver.
The 44-year-old television personality shared the devastating news through an emotional video posted to Instagram on Thursday.
In the footage, Mr Best spoke about his 73-year-old mother's condition, which was discovered just weeks ago. He said: "A few weeks ago, my beautiful, wonderful mum was diagnosed with cancer."
The reality star emphasised that his mother had always prioritised her wellbeing throughout her life.
Calum is the son of football legend George Best
|GETTY
"For as long as I can remember, she has lived her life rooted in health, fitness and wellbeing," he explained.
"But as we all know, cancer doesn't discriminate. It doesn't care where you're from, how you live, or how healthy you try to be."
Mr Best admitted the diagnosis had taken a significant emotional toll on him.
"I'll be honest, I haven't cried in years, but this has been an emotional rollercoaster I never expected to be on," he said.
Angie Best (right), in 1984
|GETTY
The former Celebrity Big Brother contestant acknowledged he had deliberated for weeks over how to share the news publicly.
He explained that when it came to his mother's health, honesty was the only thing that truly mattered.
Mr Best has launched a GoFundMe campaign to help cover the costs of specialist care. "This is incredibly hard for me to say, but financially, I can't carry this on my own," he admitted.
He urged supporters to contribute whatever they could, promising to share updates on his mother's progress throughout her treatment journey.
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George Best's other Angie included a message in the Instagram caption
|Ms Best herself shared a message through her son's Instagram page, declaring her readiness to battle the disease.
She outlined the various treatment options she is investigating, including immunotherapy, targeted chemotherapy designed to shrink tumours without destroying all her immune cells, interventional radiology, and hepatic artery infusion therapy directed at her liver.
The former fitness instructor and model explained that the fundraising would also cover living expenses, home care and travel costs associated with her treatment.
"Consultations and research all takes dosh which I don't have," Ms Best wrote.
Angie and Calum Best at George's funeral in 2005
|PA
She added that she believed sharing her experience could prove valuable, noting that statistics suggest one in two people will develop some form of cancer. "Wish me luck, Onwards and upwards Homies," she concluded.
Ms Best, who was born in Essex and worked as a fitness instructor, model and Playboy Bunny, first encountered the Manchester United and Northern Ireland football legend at a dinner party in Los Angeles in 1975. George was in the city to sign for the Los Angeles Aztecs at the time.
The couple's romance quickly attracted attention on both sides of the Atlantic. They relocated to London in 1976, though Angie later returned to America. George followed her and proposed, with the pair marrying on January 24, 1978.
Their son arrived in 1981, but the marriage did not last. The couple separated in 1982 and finalised their divorce four years later in 1986, following George's struggles with alcohol addiction and domestic violence.