Monday's FA Cup fourth round draw has thrown up a cracking encounter between Aston Villa and Newcastle as the standout fixture.
The draw took place ahead of Liverpool's third round clash with League One outfit Barnsley, giving all remaining clubs a glimpse of their next opponents on the road to Wembley.
Newcastle booked their spot after an entertaining 3-3 draw with Bournemouth that went all the way to penalties.
Whoever comes out on top in this all-Premier League showdown will face Brighton in the fifth round – the side who knocked Manchester United out at the first hurdle.
Macclesfield completed the biggest shock in FA Cup history, after they knocked out holder Crystal Palace on Saturday
| REUTERSMacclesfield pulled off what many are calling the biggest upset in FA Cup history on Saturday, sending holders Crystal Palace crashing out of the competition.
It's the stuff dreams are made of for the non-league side, and their reward is a home tie against Brentford.
The Silkmen will fancy their chances of another memorable cup run after that stunning result.
Wrexham are also hoping to continue their fairytale journey after dumping Nottingham Forest out on penalties.
Ryan Reynolds and Rob McElhenney's side will host Ipswich in what promises to be another Hollywood-worthy chapter for the Welsh club.
Wrexham triumphed over Nottingham Forest after an enthralling FA Cup clash | REUTERSArsenal, who sit top of the Premier League, had a slight wobble before thumping Portsmouth 4-1 on Sunday.
Mikel Arteta's men will welcome Wigan to the Emirates for their fourth round tie.
Chelsea enjoyed a comfortable 5-1 victory over Championship side Charlton Athletic and have been handed an away trip to Hull City.
It will see new boss Liam Rosenior make a swift return to Hull, where his managerial career started.
Manchester City recorded a remarkable 10-1 win against League Two's Exeter City – a record-breaking scoreline at the Etihad.
Pep Guardiola's side will face either Salford City or Swindon Town next.
Leicester, who lifted the trophy back in 2021, will take on Southampton following their 2-0 win over Cheltenham Town.
Chelsea boss Liam Rosenior will return to his old stomping ground when the Blues face Hull
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Leeds have been drawn against Championship side Birmingham City, while Burton Albion will host West Ham United.
Other ties include Stoke City versus Fulham, Oxford United against Sunderland, and Grimsby Town facing Wolves.
There's still one third round match left to play, with Salford City hosting Swindon Town next Tuesday evening.
All fourth round fixtures will take place across the weekend of 14th and 15th February, with TV selections to be announced in due course.
FA Cup fourth round in full
The FA Cup has already seen some huge upsets already - are there more awaiting us in the fourth round?
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Liverpool vs Brighton
Stoke City vs Fulham
Oxford United vs Sunderland
Southampton vs Leicester City
Wrexham vs Ipswich Town
Arsenal vs Wigan Athletic
Hull City vs Chelsea
Burton Albion vs West Ham United
Burnley vs Mansfield Town
Norwich City vs West Bromwich Albion
Port Vale vs Bristol City
Grimsby Town vs Wolverhampton Wanderers
Aston Villa vs Newcastle
Manchester City vs Salford City or Swindon Town
Macclesfield vs Brentford
Leeds vs Birmingham City