Ederson has been left out of Manchester City's squad for tonight's Premier League opener against Wolves at Molineux.
The Brazil international has been linked with a move away from the Etihad Stadium amid speculation that City are keen on Paris Saint-Germain goalkeeper Gianluigi Donnarumma.
James Trafford, who joined from Burnley earlier this summer, will start between the sticks instead.
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Stefan Ortega, meanwhile, is on the bench.
Ederson won't be involved in Man City's Premier League opener against Wolves on Saturday night
|PA
Turkish side Galatasaray are interested in acquiring Ederson before the summer transfer window slams shut.
But City insist their No 1 goalkeeper is missing due to illness, specifically gastroenteritis.
That's unlikely to quell the speculation over his future, especially with the links to Donnarumma intensifying in recent days.
The Italian was nothing short of sensational last term as PSG won a stunning treble under Luis Enrique.
But they've since signed Lucas Chevalier from Lille, with Enrique keen for his goalkeeper to be better with his feet.
Donnarumma was left enraged by that all and hit out at PSG in a statement earlier this week. The former AC Milan star said: “To the special Paris fans, From the first day I arrived, I gave everything – on and off the pitch – to earn my place and defend the goal of Paris Saint-Germain.
“Unfortunately, someone has decided that I can no longer be part of the group and contribute to the team’s success. I am disappointed and disheartened.
“I hope to have the opportunity to look the fans at the Parc des Princes in the eyes one more time and say goodbye as it should be done.
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Ederson has been left out of Man City's squad for their match against Wolves amid speculation linking the club with a move for Gianluigi Donnarumma
| PA"If that doesn’t happen, I want you to know that your support and affection mean the world to me, and I will never forget it.
“I will always carry with me the memory of all the emotions, the magical nights, and of you, who made me feel at home.
“To my team-mates – my second family – thank you for every battle, every laugh, every moment we shared. You will always be my brothers.
"Playing for this club and living in this city has been an immense honour.”
City have gone strong for today's match with Wolves.
Rico Lewis, John Stones, Ruben Dias and Rayan Ait-Nouri make up their back four, with Trafford in goal.
In midfield, Tijjani Reijnders and Nico Gonzalez will act as anchors - with Bernardo Silva deployed as a No 10.
And Jeremy Doku and Oscar Bobb will flank Erling Haaland in attack as the Norwegian looks to add to his stunning goal tally.
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Ederson has established himself as a Man City legend ever since his arrival back in 2017
| REUTERSCity weren't their usual selves last term, with the club forced to accept a place in the top four instead of a challenge for the Premier League title.
Whether they can win that prize back from Liverpool this term remains to be seen.