Boris Johnson branded Keir Starmer a "lawyer, not a leader" during a fiery exchange at PMQs.
The Prime Minister said the Labour leader is the "problem" with the party as he faced questions from him at PMQs.
Mr Johnson said "We love this country and we are doing everything in our power to help this country.
"Of course he wants me out of the way, the reason he wants me out of the way is because he knows this government can be trusted to deliver.
"We delivered on Brexit, he voted 48 times to take this country back into the European Union.
"We delivered the fastest vaccine rollout in Europe.
"We will deliver our plan to unite and level-up across the whole UK.
The Prime Minister was met with criticism and calls to resign in the Commons.
Lloyd Russell-Moyle, Labour (Co-op) MP for Brighton, Kemptown, demanded "I would prefer be led by a lawyer than a liar. Will he now resign?"
Boris Johnson responded, "he plainly doesn't know what he's talking about.'
SNP Westminster leader Ian Blackford said every moment Boris Johnson stays “he is dragging out the agony for families who are reminded of the sacrifices they made”.
Mr Blackford said: “At the heart of this matter we have a Prime Minister who is being investigated by the police for breaking his own laws. Absolutely unprecedented. A man who demeans the office of Prime Minister. This is the latest in a rap sheet that is already a mile long.
“Illegally proroguing Parliament, misleading the House, decorating with dodgy cash, partying while the public suffered. Every moment he stays he is dragging out the agony for families who are reminded of the sacrifices they made, and dragging his party further through the dirt.
“The public knows it, the House knows it, even his own MPs know it. When will the Prime Minister cop on and go?”
Boris Johnson said: “He made the same point last week. He’s wrong then, he’s wrong now.”
He added: “It is precisely because I enjoy cooperating with him so much and with all his Scottish colleagues that I have absolutely no intention of doing what he suggests.”