The Prime Minister's Office was placed under lockdown as police moved Downing Street staff into "secure rooms".
A police cordon was erected on Parliament Street this afternoon while officers investigate an "abandoned vehicle".
Four police vans were also blocking the route to the official residence of Sir Keir Starmer.
The incident has since been resolved, police said in a later update.
A police cordon has been erected on Parliament Street this afternoon while officers investigate an 'abandoned vehicle'
GB News
The Metropolitan police said the cordon had been put in place as a “precautionary measure”.
A spokesman for City of Westminster Police said at the time: "A cordon is in place at the southern end of Whitehall as a precautionary measure while officers investigate an abandoned vehicle in the vicinity of Downing Street.
"It is not linked to a separate road traffic collision involving a coach and a pedestrian in nearby Abingdon Street."
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The lockdown followed a road traffic collision involving a pedestrian and a bus on nearby Abingdon Street earlier today.
The condition of the person is currently unknown, but is is believed they were trapped underneath the bus.
A London Ambulance Service spokesperson said: "We were called at 1.29pm today (June 11) to reports of a road traffic collision on Dean's Yard, Westminster.
"We sent resources to the scene, including an ambulance crew, paramedics in fast response cars, an incident response officer and a clinical team manager. We also dispatched London’s Air Ambulance.
Police officer blocking the route to the official residence of Sir Keir Starmer
GB News
"We treated a man for a head injury and took him to a major trauma centre by road."
Both incidents forced traffic to be halted in the area.
Emergency services advised motorists to only drive through the area if absolutely necessary.
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